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Moreover, COL II and SOX9 expression in the PKG hydrogel-treated group were elevated by 3.6 and 3.5-fold compared to the control group, respectively, owing to the chondrogenesis property of KGN

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Microdosing refers to the practice of consuming a low dose of GLP-1 drugs (off-label) instead of the standard therapeutic dose to achieve mild weight loss or appetite benefits with fewer side effects at a lower cost

While short-term increases in cortisol support adaptive energy regulation, chronic elevationsespecially from prolonged or frequent fastingmay promote muscle catabolism, reduce metabolic health, and impair insulin sensitivity [44]