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Study approval All animal experiments were performed in accordance with the National Institutes of Healths Guide for the Care and Use of Laboratory Animals (NIH publication no

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Many people maintain normal energy levels throughout treatment, and some actually report improved energy compared to before starting medication, particularly after several months when weight loss benefits accumulate

In the second subgroup (ALC add-on vs the same background drug), Gavrilova et al 19 observed AEs in 35% with ALC add-on versus 45% with antidepressant alone, and Ramezani et al 20 reported AEs in three patients (1 in ALC + sertraline, 2 in sertraline + placebo)