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Foam indicates protein denaturation

Exogenous spiked-in miRNAs were more consistent between samples

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in total 9470 cells (3149 for hLMNA-WT and 6321 for hLMNA-R482L) were taken for further analysis

The authors of the study concluded that the GLP-1 receptor agonist lixisenatide had a three-point beneficial effect, when compared with placebo, in the change over a 12-month period from a baseline value of approximately 15 points on a 132-point scale measuring motor disability. The active arm improved 0.04 points in the lixisenatide group and worsened 3.04 points in the placebo group