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A Novo Nordisk spokesperson pointed out that NAION is not listed on approved labels as an adverse drug reaction for the marketed formulations of semaglutide. They also noted limitations in the Mass Eye and Ear study, such as its small and non-randomized sample group

Some guidelines recommend holding GLP-1 receptor agonists before procedures requiring sedation or general anesthesia to reduce the risk of aspiration, though specific recommendations may vary based on the procedure type and individual patient factors

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9 (download XLSX Source data for Extended Data Fig

At the same time, the face mask strongly nourishes, deeply moisturizes and smoothes the epidermis