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Consistent with these effects, GLP-1 RAs have been associated with substantial weight loss in clinical trials, leading to FDA approval of two of these agents liraglutide and semaglutide for chronic weight management in adults with obesity or with overweight and at least one weight-related comorbidity

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Recheck your TSH and free T4 levels 68 weeks after starting treatment and work with your doctor to adjust doses if needed

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