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and GIP receptors have also been demonstrated to activate phosphoinositide 3-kinase (PI3K) and its downstream effector Akt, which modulates mitochondrial function, metabolism, and cell survival

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Dutasteride androgen blocking Dutasteride is a dual 5-alpha reductase inhibitor that blocks the conversion of testosterone to dihydrotestosterone (DHT) the primary hormone responsible for follicle miniaturisation in androgenetic alopecia