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High RHOJ expressing bladder cancer may exhibit enhanced immune responses in the TME, possibly associated with an increased monocyte-to-lymphocyte ratio

This was exemplified here by the fact that increased GSH production in the presence of 5-FOA (counter-selective for URA3 expression) appeared to be a non-specific response to 5-FOA, evident also in the control strain expressing URA3 behind pURA3 , rather than selection based on phenotypic heterogeneity as intended in this proof-of-principle study

Concurrent use with an insulin secretagogue or insulin may raise the risk of hypoglycemia

SDP has received research funding from AstraZeneca, Boehringer Ingelheim, Novartis Pharmaceuticals Co., and Merck Sharpe & Dohme, and is a consultant for or has received honoraria from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, GlaxoSmithKline, Janssen Pharmaceuticals, Laboratoires Servier, Merck Sharp & Dohme, Novartis Pharmaceuticals Co., Novo Nordisk, Sanofi, and Takeda