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mB12/LDFA and HDFA did not significantly change SAM, SAH or the SAM/SAH ratio

Astrocytes can at least temporarily switch to the glycolytic pathway to support their own energetics, and can use their glycogen pool (of which they are the sole possessors in the CNS 205,206 ) to produce lactate and support energy substrate-deprived neurones

It is not a final decision

This parallel makes Dihexa an interesting crossover compound for researchers investigating whether repair mechanisms in the periphery (tendons, gut) share common signaling logic with repair mechanisms in the brain (synapses, dendrites)

It also helps buffer toxic acyl-CoA metabolites and supports mitochondrial health and function