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Nutritional Support for Phase 1 Detoxification Appropriate nutritional support is essential to ensure Phase 1 detoxification proceeds efficiently without increasing oxidative burden or metabolic stress

GLP-1 agonists (semaglutide, tirzepatide) reduce appetite and slow gastric emptying to create caloric deficits, while AOD-9604 and 5-Amino-1MQ directly enhance fat mobilisation and oxidation without affecting satiety signalling

These peptides represent a novel class of therapeutic agents that may offer alternatives to traditional treatment approaches for various pathological conditions

Overall, 50 docking results with 6 different histone proteins were investigated

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