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Phase 2 data of retatrutide, a similar triple agonist developed by Eli Lilly, has shown a remarkable 24% weight loss after 48 wk of treatment, without reaching a plateau (1)

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Discontinuing treatment should be discussed with a medical practitioner, as lifestyle changes may be needed to maintain results

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Abstract Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-1), declines over time until only low levels can be detected in individuals aged 60 years