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Most GLP-1 medications provide guidance for missed doses in the prescribing information

However, malignant tumors subvert arginine metabolic homeostasis through metabolic reprogramming: for example, hepatocellular carcinoma (HCC), which lacks the ability to synthesize arginine on its own, significantly enhances the uptake efficiency by up-regulating arginine transport proteins (e.g., SLC6A14 and CAT-1) and inhibits the conversion of arginine to polyamines, resulting in the accumulation of high concentrations of arginine in the tumor microenvironment(Mossmann et al

Follow-up Re-check blood pressure, resting heart rate, and metabolic markers after 4-8 weeks or sooner if symptoms change

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10.1159/000093982 [DOI] [PubMed] [Google Scholar] Seven A., Civelek S., Inci E., Inci F., Korkut N., Burcak G