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Another limitation was narrow sample size, which although proved to be statistically adequate, did not allow for a more in-depth analysis of the studied variables

Validated liquid chromatography mass spectrometry (LC-MS/MS) assays were used to investigate plasma concentrations of the four victim drugs: ethinylestradiol, levonorgestrel, furosemide and rosuvastatin

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It should return to normal within a day or two once the food or supplement leaves the body

However, this introduces unpredictability: the same dose could produce significantly higher plasma levels than intended, and the effect varies by inhibitor potency