For best results, we recommend taking 2 capsules, with meals
Because it can be quite strong, it is usually recommended for occasional use rather than daily maintenance unless otherwise directed by a provider
These can sometimes lead to dehydration, which may strain the kidneys

the expected effect size is small and the onset is slow - Avoid antidepressants in bipolar depression presenting with subtle increased psychomotor tempo, pressured speech and racing thoughts due to the increased risk of switch and potentially rapid cycling - Consider ETC as a viable option for the treatment of bipolar depression resistant to pharmacological treatment - Never treat with antidepressants without a mood stabiliser - If an antidepressant is added, use mainly SSRIs due to their low switch rate - If an antidepressant is used in maintenance treatment, the occurrence of manic/mixed symptoms should be monitored carefully The above recommendation is consistent with current Danish guidelines for the pharmacological treatment of bipolar disorder [42], which recommend lithium, quetiapine and lamotrigine as first-line agents for bipolar I disorder, current depressive episode, in at least 70% of patients, and for bipolar II disorder, current depressive episode, in at least 60%

Clinical trials found that people who took semaglutide lost an average of 10% more body weight than those who were given a placebo over one year of treatment