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GLP-1 medications dull normal thirst signals, reduce the water you usually absorb from food, and can trigger vomiting or diarrhea, so meeting these higher daily fluid goals is essential to prevent headaches, dizziness, kidney strain, and the constipation many users notice in the first few weeks

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"The use of these drugs has exploded throughout industrialised countries and they have provided very significant benefits in many ways, but future discussions between a patient and their physician should include NAION as a potential risk," Dr Joseph Rizzo, one of the studys authors and director of the neuro-ophthalmology service at Massachusetts Eye and Ear, where the research took place, said in a statement