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It is also worth noting that APAP is used in combination with other drugs, particularly opioids and diphenhydramine, without public awareness (Rajaram and Subramanian, 2018)

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While PCGrimAge change was not linked to anthropometric or metabolic outcomes, an increase in telomere length (PCDNAmTL) was associated with improved gait speed, indicating that epigenetic telomere preservation may parallel enhancements in physical function