The study also confirmed that AOD9604 works by inhibiting fat synthesis in liver and fat cells, providing additional mechanistic insight into how the peptide promotes metabolic health
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To put it in context, nicotinamide has shown signs of liver toxicity only at doses around 3,000 mg per day or higher
The combination creates a context where AOD 9604s lipolytic effect is occurring simultaneously with GH-stimulated protein synthesis and recovery, theoretically allowing fat loss and lean mass preservation to happen in parallel