A substantial proportion of patients continue to progress to advanced CKD or ESKD despite standard therapy ( In the field of procedural cell death, ferroptosis is a regulated form of cell death that depends on iron ions and lipid peroxidation, which is considered to be related to the development of a variety of diseases, including neurodegenerative diseases, cancer, acute kidney injury (AKI) and chronic kidney disease ( GPX4 ) expression in DKD kidney tissue, supporting ferroptosis as a potential mechanistic link between tubular injury, oxidative stress, and renal fibrosis ( From the perspective of intervention, identifying ferroptosis regulators in clinically available drugs is considered a strategy with great potential for transformation
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Who should avoid IV drip therapy
