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The db/db mouse is a well-established and widely used model of obesity-associated and diabetes-related fatty liver disease It exhibits key pathological features that resemble human diabetic MASLD, including severe insulin resistance, hyperglycemia, hyperlipidemia and hepatic steatosis [32]

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Studies show GLP-1s help decrease weight, improve metabolic complications, lower flares and stiffness, and may slow joint damage when combined with DMARDs or biologics