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Oxidative Stress and Redox Biology (Copper-Dependent) Due to coppers involvement in active redox chemistry and copper-dependent enzymatic processes, GHK-Cu is employed to study endpoints related to reactive oxygen species (ROS), antioxidant enzyme regulation, and metal ion homeostasis

doi:10.1186/1750-1172-5-39 2Khalili B, Bahna SL

Specifically, HP and PRDX4 exert antioxidant properties, thus their overexpression is known to be involved in the scavenging effect against the overproduction of ROS

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2000) and its inhibition (for instance by S-nitrosylation) may result in anti-inflammatory effects (Morris et al