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Furthermore, the circadian dysfunction in the Tg2576 model has been associated with compromised GABAergic signaling in the suprachiasmatic nucleus (SCN), a critical structure for orchestrating circadian rhythms (Eeza et al., 2021)

Sivakumar J, Chong L, Ward S, Sutherland TR, Read M, Hii MW

The increase in serum LDH is associated with poor survival, one of the consequences of melanoma cells outgrowing and surpassing the blood supply (124)