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Semaglutide is not recommended during pregnancy, and due to its long washout period, the MHRA advises discontinuing Ozempic at least two months before a planned pregnancy to ensure the medication is cleared from the system
GLP-1 agonists, such as semaglutide (Ozempic), also act in the brain and have shown promising neuroprotective effects in both human trials and animal models
However, selling or using it for human consumption is illegal and strongly discouraged by the FDA
They recommend a low-carbohydrate, high-protein diet prior to initiating medication
Patients should contact their healthcare provider if cold intolerance is accompanied by severe fatigue, hair thinning or loss, persistent constipation, cognitive impairment, or depression , as these may indicate thyroid dysfunction requiring laboratory assessment
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