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Long-term human safety data remains limited due to the compounds regulatory status

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Increased skeletal muscle oxidative capacity is associated with improved glucose tolerance and insulin sensitivity and reduced obesity (Donnelly et al., 2013), thus we hypothesized that synthetic ERR agonists that increase their transcriptional activity above their very high constitutive level may hold significant utility in the treatment of metabolic syndrome

The word amino in its chemical name refers to an amino functional group attached to the quinolinium ring