This thermogenic effect increases calorie burning, contributing to greater weight loss
demonstrated that exogenous IGF-1 administration reduces functional deficits and accelerates recovery in a rat Achilles tendon injury model ( In vitro studies further support its therapeutic potential, showing that IGF-1 modulates inflammatory responses, stimulates tenocyte proliferation and migration, and enhances collagen synthesis ( 2 Materials and methods Approximately 90% of the papers mentioned in this review (total number of papers included in this review: 103) were found by a search in the Web of Science/Google Scholar databases using the keywords tendon injury, IGF-1, tendon regenerative healing, tendon repair, tenocyte, mechanisms (the search was performed during the period of May to September 2024 and only literature written in English was reviewed) (Figure 1)
These include the vial of semaglutide, sterile water for injection, alcohol swabs, syringes, and needles
D-RL, J-YJ, and H-CZ revised the manuscript
Patients on both therapies often experience synergistic metabolic improvements: testosterone supports muscle preservation and strength during weight loss, while GLP-1 medications accelerate fat loss and improve cardiometabolic markers
