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Patients with Significant Visceral Adiposity and Cardiovascular Risk: Tirzepatide's disproportionate VAT reduction is specifically relevant for patients whose primary cardiometabolic risk driver is visceral fat patients with central obesity, elevated triglycerides, low HDL, elevated fasting glucose, and hypertension meeting metabolic syndrome criteria

There are also few studies concerning the safety of GLP-1RA implementation in neuropsychiatric diseases

GLP-1 therapies promote weight loss by targeting appetite and metabolism

Dosage and forms Tirzepatide and semaglutide differ in their forms and usual doses

In 2021, the FDA also authorized a higher dosage (2mg/weekly) for the same application [4]