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Enhances periodontal wound healing, as reported by clinicians
In pigs, which are considered tolerant concerning iodine excess, high iodine doses up to 10 mg/kg caused a significant downregulation of NIS in the thyroid gland and, simultaneously, it decreased mRNA expression of clue antioxidative enzymes, such as SOD and GPx, either in the liver or in the kidney or in muscles (target tissues of thyroid hormone action), however without affecting lipid peroxidation [196]
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Cystatin C is associated with risk of venous thromboembolism in subjects with normal kidney function--the Tromso study
Thus, sinus tract formation and early fibrosis result as the outcome of the combined action of inflammation circuit, tissue disruption by MMPs and TIMPs with the simultaneous overproduction of ECM and pro-fibrotic components (Fig
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