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In addition, it supports electrolyte balance and the maintenance of normal bones

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164 Although these facts suggest that hemostatic problems are common in patients with liver disease, discordance is often noted between degree of abnormality of laboratory tests of coagulation and clinical evidence of bleeding.260,446,455 Even in patients bleeding from esophageal varices and having prolonged clotting times, administration of blood components (including activated factor VII) was not associated with any clinical difference in degree of bleeding or need for blood transfusions

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This allows the heart and kidneys to reap the established longevity and metabolic benefits of the SGLT2 inhibitor without the penalty of stiffer, constricted blood vessels