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Notably, in obese individuals, a small fraction of short-chain fatty acids can be transported from the mitochondria to feed DNL, but the biological significance of this pathway needs more investigation 9

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Learn what the evidence says, the risks involved, and why clinicians advise caution

According to the Journal of Health, Population and Nutrition, anything from sleep deprivation to contraceptive use can make trimming the fat far more complex than calories in versus calories out