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Common contributors Seasonal or environmental allergies Chronic inflammatory activity Recovery from infection Medication effects Smoking or irritant exposure Findings needing closer review Persistent elevation Markedly elevated absolute basophils Abnormal platelets, hemoglobin or other white cells Weight loss, fever, night sweats or enlarged spleen New bruising, fatigue or recurrent infections Basophils, Histamine and Symptoms Allergy Itching, hives, congestion, sneezing, watery eyes and flushing

Diarrhea or Constipation: Gastrointestinal issues are common with injectable forms as well

Some patients feel mild lightheadedness if the drip is too fast

J Cell Sci 115:20532065 Petit FM, Serres C, Bourgeon F et al (2013) Identification of sperm head proteins involved in zona pellucida binding

Antibody Development A few patients developed anti-Cagrilintide antibodies on treatment