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Recreational activities including tennis, golf, and gardening also contribute

General cell culture and imaging The HeLa cell line used in this study was purchased from American Type Culture Collection (ATCC) and grown in DMEM (Gibco, 11965) media supplemented with 10% FBS and 1% 1003 Pen Strep (Gibco)

Orforglipron is manufactured by Eli Lilly, the same pharmaceutical company that produces Mounjaro (tirzepatide), which is currently one of the most effective weight-loss treatments available in the UK

The results showed that abdominal fat percentage decreased by 2.6, 2.8, and 6.1 percentage points in the exercise, Lira, and combination groups compared to placebo

Rotate injection sites each week to avoid lipohypertrophy (thickened fat deposits) that can reduce medication absorption