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D2R agonist, such as bromocriptine, suppresses PRL secretion to decrease HPRL and to normalize the dopaminergic system in SLE, through the pertussis toxin (PTX)-sensitive Gi/o and PTX-insensitive Gz proteins, as well as a G protein-independent, -arrestin/glycogen synthase kinase-3-dependent pathway (150, 151)

102 Jin et al

Organ Stress and Toxicity One of BPC-157s strengths is its organ-protective effect , particularly in the gut, liver, and brain

BCL-2 improves oxidative phosphorylation and modulates adenine nucleotide translocation in mitochondria of cells harboring mutant mtDNA

doi:10.1093/toxres/tfac050 Hashmi, M