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This indicates the need for more research to determine guidelines that can ensure GLP-1 RAs are used safely and effectively in this group of women, including those with type 2 diabetes, obesity or overweight, and polycystic ovary syndrome

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To address this, we performed transcription profiling using Bru-seq and identified genes involved in cellular stress response, steroid metabolism, transcription and cytoskeleton organization as significantly altered by both GSTO1 siRNA and C1-27

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