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In the efficacy study with obese monkeys, the dosing regimen that produced the 11% body weight loss and 39% fat deposit reduction over 28 days was not precisely detailed in all publications, but researchers described managing doses to balance efficacy against renal function

Comparing the schistosomicidal activity against juvenile worms with that of PZQ reported in previous in vivo studies 61 , the inhibitors reported herein show superior schistosomicidal activity to PZQ at the worm developmental stage in mice

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J., Oshima, T