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We further observed that the procognitive effects of dihexa were blocked by Hinge, an HGF/MET dimerization antagonist, indicating these actions are mediated by HGF/MET signaling pathways

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Interestingly, polycatechol promotes liquid-liquid phase separation of tau and regulates its intermolecular interactions to inhibit the formation of toxic tau aggregates, providing a conceptually innovative approach for treating AD