ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntingtons disease
The processed snRNA-seq in AAV- Pcsk5 and AAV-Ctrl mice and bulk RNA sequencing in HUVECs data are available at figshare ( Other previously published patient datasets used in the study can be accessed with the following accession numbers: GSE184986, GSE132143, GSE41166, GSE270788, GSE110209, GSE153481, Figures 2A, G, 8A, D, S3A, and S4A were generated using BioRender under a paid subscription (agreement numbers: AP29BK99A0, SX29G17FUG, YC29H5H18H, IA29H5HWKF, LD29H5HPI5, GI29H5HIIC)
CJC-1295 and Somatotroph Biology The GHRH-receptor signalling pathway activated by CJC-1295 stimulates adenylate cyclase, increasing intracellular cAMP and engaging PKA-linked transcriptional regulation of the GH gene in somatotroph cells with in vivo research confirming increased pituitary RNA, GH mRNA, and somatotroph cell number following administration, establishing that GHRH-class secretagogues act on multiple levels of GH axis biology beyond simple acute secretion
Unanticipated Residual Gastric Contents in an Appropriately Fasted Pediatric Patient on GLP-1 Receptor Agonist Therapy: A Case Report and Review of Perioperative Considerations
Clarkson et al, 1996
