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However, gastrointestinal adverse events and SAEs resulting in drug discontinuation were similar in both groups

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Additionally, patient demographics such as other or unknown race and missing sex in datasets can impact study findings and generalizability

In apolipoprotein E knockout (ApoE - / - ) mouse models, it significantly reduces the area of atherosclerotic plaques and the formation of lipid necrotic cores, concurrently decreasing serum inflammatory factors (e.g., interleukin6, tumor necrosis factor) [368]