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doi:10.1016/j.jbiosc.2016.12.011 Schmitt B, Vicenzi M, Garrel C, Denis FM (2015) Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: a comparative crossover study

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The pathways activated by TrkA include Ras, Rac, PI3K, and PLC-1, which in turn activate mitogen-activated protein kinase (MAPK) cascades and Akt to generate inositol triphosphate and diacylglycerol (Sofroniew et al., 2001)

Oxidative stress is also a natural process, but like inflammation, when its out of control, meaning in this case, when theres an imbalance of free radicals compared to antioxidants in the body, cell and tissue damage can occur