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It does not seem to be entirely driven by tissue damage, as highlighted by the discordance between pain and structural changes in OA joints 38

The effect of serum -human chorionic gonadotropin on pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis

First, researchers should investigate the efficacy of different EA waveforms, comparing intermittent and dense-disperse waveforms, along with exploring the effectiveness of various EA frequencies, such as 1 Hz versus 100 Hz