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Pharmacodynamic (PD) biomarkers are defined as the biological response to a drug treatment (Sawyers 2008) and either are treatment specific or may represent endogenous phenotype changes in a subject due to a drug treatment (Beger and Colatsky 2011)

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10.1016/j.mce.2012.05.005 58 IrreraN.PizzinoG.DAnnaR.VaccaroM.ArcoraciV.SquadritoF.et al (2017)

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