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Formulated as pre-dosed oral capsules , this presentation offers a convenient, ready-to-use format for research applications, with consistent strength per capsule and straightforward handling under laboratory conditions

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The samples were fixed with 4% PFA at room temperature for 30 min, permeabilized with 0.1% Triton-100 at room temperature for 15 min, and blocked with 5% BSA solution at 37 C for 1 h

Acknowledgements We are grateful to all participants and acknowledge the support of the members of the RECAP study who contributed considerably to the data collection