Why it matters: A fast weight change may reflect fluid, glucose, or illness rather than fat loss
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Hoffmann, Mohammed Hammoda, Anurag Agarwal, Edward Farley-Hills Drafting of the manuscript: Suhaib Ahmad, Bethany Taylor Critical review of the manuscript for important intellectual content: Suhaib Ahmad, Bethany Taylor, Wah Yang, Sjaak Pouwels, Graham Whiteley, Danielle Wilkinson, Ahmed Ahmed, Andrew Beamish, Mahmoud Al-Ardah, Rebecca V
Glucose excursions the glucagon component can raise fasting glucose in some patients without diabetes
Some experts suggest an induction-maintenance model : initiating treatment with subcutaneous injections for rapid initial weight loss, followed by long-term oral maintenance