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Other reported side effects were mostly local to the injection site, including pain, the formation of nodules, swelling, redness, itching, a warm sensation, and discoloration

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Angiogenesis support (new blood-vessel signaling) via VEGFR2 Akt eNOS (nitric oxide) pathways

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Conclusion The mechanistic throughline across BPC-157 research angiogenesis, nitric oxide signaling, FAK/paxillin-linked cell migration, and MAPK/ERK1/2 activity is consistent across tendon, muscle, and other injury models in rats