Long-term side effects linked to Saxenda: Gastroparesis (stomach paralysis) Ileus (intestinal blockages) Gallbladder problems, including gallstones (symptoms include severe abdominal pain, diarrhea, pale-colored stool, fever, nausea, vomiting, jaundice) Increased heart rate (heart palpitations, chest pain) Pancreatitis (sudden upper abdominal pain, persistent severe burning pain in the abdomen, vomiting) Suicidal thoughts or behavior (new or worsening depression, thoughts about harming yourself or ending your life, changes in mood or behavior) Kidney failure Low blood sugar Risk of thyroid cancer Severe allergic reaction Saxenda and Vision Loss A recent study in JAMAs Ophthalmology found semaglutide drugs could cause a specific sort of eye condition called NAION
A post-hoc age subgroup analysis of SURMOUNT1 further showed that tirzepatide reduced fat mass by 3336% and lean mass by 1011% across all age groups, resulting in improved body composition
As a result, sermorelin has several clinical indications and applications related to GHRH/GH deficiency (GHD) including diagnostic evaluation of pituitary function and management of age-related, maladaptive changes in body composition such as reduced lean body mass (muscle), increased total and visceral fat, and decreased bone mass
This landmark study generated the initial excitement around the compound
doi: 10.3389/fphys.2020.00270 381
