It's to provide researchers with the highest quality options and the expert knowledge to help them make the best choice for their work
[DOI] [Google Scholar] 98.Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Jagic V., Turkovic B., Rotkvic I., Mise S., Zoricic I., et al
Bordwell, private communication
1 Introduction Autoimmune diseases (ADs) arise from the immune systems aberrant response against self-tissues, encompassing diverse conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), type 1 diabetes (T1D), and primary biliary cholangitis (PBC) ( Mounting evidence suggests that gut microbiota and its metabolites play a key role in host health and diverse diseases, such as obesity, depression, sclerosis, kidney disease, and dialysis ( At present, in the interest of reshaping the disordered intestinal immune activity in the disease state and alleviating the disease, people propose a series of flora-related immunotherapies based on the close interaction between the intestinal immune system and the flora ( Clostridium , a genus of anaerobic, Gram-positive, thick-walled bacteria, constitutes a dominant component of the healthy gut microbiota ( Clostridium species may confer clinical benefits across multiple ADs ( 2 Classification and sources of Clostridium as probiotics The intestinal clostridia as probiotics mainly contain Clostridium butyricum ( CB ), Faecalibacterium prausnitzii ( FP ), Clostridium cocleatum , etc
This approach is seen as simpler and avoids the alleged perverse incentives created by past high/low-cost buckets
