Oxidative stress has been implicated in a number of diseases which include atherosclerosis, pulmonary fibrosis, cancer, Parkinson's disease, multiple sclerosis, and aging[6]
MHY-1485 (mTOR agonist), PHA-665752 (c-Met inhibitor), and PF-04691502 (mTOR inhibitor) were purchased from MedChem Express (Monmouth Junction, NJ, USA)
Astaxanthin prevents bone loss in osteoporotic rats with palmitic acid through suppressing oxidative stress
Hepatoma Res 4:39 Gao T, Wang T, Wang Z, Cao J, Dong Y, Chen Y (2021) Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/ROR/NF-B signaling pathways
Despite discoveries in treatments and diagnosis of these diseases as well as the modifications of the old approaches, these diseases are still quite prevalent with high socio-economic impacts