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Gut-derived TMAO induces apoptosis by increasing intracellular mROS levels and further promoting NLRP3 assembly activation, with the underlying mechanism being the regulation of the intracellular mROS-NLRP3 axis to activate cytokinesis and release inflammatory factors, thus promoting DKD (Yi et al., 2023)

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Supports Lean Muscle Preservation During Caloric Deficits One of the most documented and practically important properties of CLA in clinical research is its role in lean muscle mass preservation during caloric restriction