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I have seen more significant [gastrointestinal] side effects with oral semaglutide than with injectable, Moreno said, noting that he wonders what differences in side effects may occur when using such high doses of semaglutide compared with [the] injectable dose. In the trial, Novo Nordisk said, the vast majority of side effects of oral semaglutide were mild to moderate and diminished over time. All GLP-1 medications are associated with side effects including nausea, vomiting and abdominal pain, although not all patients experience them

If you are considering switching, the switching from semaglutide to tirzepatide guide and the semaglutide to tirzepatide conversion chart provide the dosing equivalencies you need

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doi: 10.1007/s001250100548 27 ObozaPOgarekNOlszanecka-GlinianowiczMKocelakP

10.5009/gnl18490 67 SikiricP.DrmicD.SeverM.KlicekR.BlagaicA