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Vitamin B12 is also essential for maintaining the integrity of the myelin sheath, which protects nerve cells and ensures efficient nerve signal transmission (6)

3, 4, 5 However, it is the paracellular pathway, regulated by the tight junction (TJ), that is responsible for the greatest degree of apical cellcell adhesion, 6, 7 and which has received the most attention for its role in regulating mucosal permeability under normal and pathological conditions

Because 5-MTHF is a reduced form of folic acid that does not require conversion by dihydrofolate reductase, some direct effects may be attributable to redox mechanisms that are not seen when oral folic acid is used to increase plasma folate levels [58,59]

For the body to actually rebuild and recover, it needs adequate nutritional support - amino acids, minerals, and overall metabolic balance