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24 This can be due to differences in the specific drug used, the dosage, the duration of the study, the characteristics of the participants (age, baseline health) 9 , the methods used to measure body composition (DXA, BIA, MRI all have different strengths and weaknesses) 16 , and whether interventions like dietary counseling (especially protein emphasis) and exercise were included

Insurance coverage of prescription drugs is difficult to predict, as each health insurance company creates its own deductibles, formularies, and preferred medications within drug classes and indications

The combination could theoretically produce additive appetite suppression, though formal studies are needed

The researchers adjusted for several factors, including BMI and HbA1c at baseline, Social Vulnerability Index, sex, age, race and ethnicity and insulin use history

However, research has also seen increased risks across the GLP-1 class