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7.2 Safety data from clinical studies Current studies indicate that both NSP inhibitory effects and skin symptom occurrence require high levels of DPP1 inhibition (Korkmaz et al., 2010

Placebo-Controlled Studies With DPP-4 Inhibition as Add-on to Ongoing Exogenous Insulin Therapy Sitagliptin, vildagliptin, saxagliptin, alogliptin, and linagliptin were also examined when added to on-going therapy with insulin in subjects with type 2 diabetes in 2426 week placebo-controlled studies with a total number of 3,196 subjects [Table 2

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25 Faria MHG, Dria-Netto RH, Osugue GJ, Queiroz L de S, Chaddad-Neto FE

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