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CTX conjugation enhanced cellular uptake in U87MG and C6 glioma cells by 3.5-fold after 4 h and reduced cell viability to 42% 3.8% compared to 61% 4.5% for non-targeted nanoparticles, with a twofold lower IC

10.1016/j.mrfmmm.2004.04.021 Mutat

Gradual tapering can reduce rapid weight regain, allowing the body to adapt as appetite-regulating effects diminish

IV delivery changes the equation